41 research outputs found

    Optimal Investment with Stopping in Finite Horizon

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    In this paper, we investigate dynamic optimization problems featuring both stochastic control and optimal stopping in a finite time horizon. The paper aims to develop new methodologies, which are significantly different from those of mixed dynamic optimal control and stopping problems in the existing literature, to study a manager's decision. We formulate our model to a free boundary problem of a fully nonlinear equation. Furthermore, by means of a dual transformation for the above problem, we convert the above problem to a new free boundary problem of a linear equation. Finally, we apply the theoretical results to challenging, yet practically relevant and important, risk-sensitive problems in wealth management to obtain the properties of the optimal strategy and the right time to achieve a certain level over a finite time investment horizon

    Stripe formation in bacterial systems with density-suppressed motility

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    Engineered bacteria in which motility is reduced by local cell density generate periodic stripes of high and low density when spotted on agar plates. We study theoretically the origin and mechanism of this process in a kinetic model that includes growth and density-suppressed motility of the cells. The spreading of a region of immotile cells into an initially cell-free region is analyzed. From the calculated front profile we provide an analytic ansatz to determine the phase boundary between the stripe and the no-stripe phases. The influence of various parameters on the phase boundary is discussed.Comment: 5 pages, 3 figures. Phys. Rev. Lett. in press (2012

    Vagus nerve stimulation for pharmacoresistant epilepsy secondary to encephalomalacia: A single-center retrospective study

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    ObjectiveVagus nerve stimulation (VNS) is an adjunctive treatment for pharmacoresistant epilepsy. Encephalomalacia is one of the most common MRI findings in the preoperative evaluation of patients with pharmacoresistant epilepsy. This is the first study that aimed to determine the effectiveness of VNS for pharmacoresistant epilepsy secondary to encephalomalacia and evaluate the potential predictors of VNS effectiveness.MethodsWe retrospectively analyzed the seizure outcomes of VNS with at least 1 year of follow-up in all patients with pharmacoresistant epilepsy secondary to encephalomalacia. Based on the effectiveness of VNS (≥50% or <50% reduction in seizure frequency), patients were divided into two subgroups: responders and non-responders. Preoperative data were analyzed to screen for potential predictors of VNS effectiveness.ResultsA total of 93 patients with epilepsy secondary to encephalomalacia who underwent VNS therapy were recruited. Responders were found in 64.5% of patients, and 16.1% of patients achieved seizure freedom at the last follow-up. In addition, the responder rate increased over time, with 36.6, 50.5, 64.5, and 65.4% at the 3-, 6-, 12-, and 24-month follow-ups, respectively. After multivariate analysis, seizure onset in adults (>18 years old) (OR: 0.236, 95%CI: 0.059–0.949) was found to be a positive predictor, and the bilateral interictal epileptic discharges (IEDs) (OR: 3.397, 95%CI: 1.148–10.054) and the bilateral encephalomalacia on MRI (OR: 3.193, 95%CI: 1.217–8.381) were found to be negative predictors of VNS effectiveness.ConclusionThe results demonstrated the effectiveness and safety of VNS therapy in patients with pharmacoresistant epilepsy secondary to encephalomalacia. Patients with seizure onset in adults (>18 years old), unilateral IEDs, or unilateral encephalomalacia on MRI were found to have better seizure outcomes after VNS therapy

    Investment and consumption problem in finite time with consumption constraint

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    In this paper, we consider an investment-consumption problem where the consumption is subject to an upper limit. This upper limit on consumption may reflect the following fact. Investors may have to finance their consumption first by using credits then pay the balance by cashing out part of their portfolio in the stock market. Credit companies set up an upper limit for the credit, thus imposing an upper bound for consumption. We also set up our model in finite horizon, which makes the problem much harder due to the loss of stationary when T < ∞. We prove that the above described problem is equivalent to a free boundary problem of nonlinear parabolic equations. We aim to characterize explicitly the free boundary by applying a dual transformation technique to convert the original nonlinear parabolic equation to a linear differential equation. This trick allows us to characterize explicitly the free boundary and the optimal consumption strategy. We also prove that the regularity of the value function, which is critical for the application of Ito formula

    Finding an expert: a model recommendation system

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    With the rapid proliferation of information technology, the increasing amount of information available has posted significant challenges on relevant information discovery for the users. An alternative way is to find an expert with specific expertise. Expert recommendation is important in variety of contexts ranging from industry to academia. Information retrieval methods or graph-based methods have been proposed to approach this problem in previous research while some important contextual factors are ignored. In this paper, considering the factors of topic relevance, expert quality, and researcher connectivity, we propose a novel researcher modeling approach to recommend experts in scientific communities. The proposed method has been implemented in ScholarMate (www.scholarmate.com), an online research social network platform. The preliminary experiment is conducted and the evaluation results exhibit that the proposed method is more effective than baseline methods

    Evaluation method of water quality for river based on multi-spectral remote sensing data

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    With the rapid development of the regional economy, water pollution has gradually become an environmental problem that cannot be ignored. As an important water source in central China, the Han River should strengthen water quality monitoring and management in order to ensure the sustainable development of watershed and related areas. Taking typical sections of middle and lower reaches of the Han River as the study area, this paper focuses on rapid river water quality assessment using multispectral remote sensing images. Based on measured water quality data and synchronous spatial high and medium-resolution remote sensing data (multi-spectral data of ZY3 and HJ1A) in 2013, neural network algorithm is used to establish water quality index retrieval model for the study area, and then water quality status is assessed accordingly. The results show that BP neural network retrieval model of water quality index that is established based on multispectral data of ZY3 satellite has higher accuracy and that its assessment results are of high credibility and strong applicability, which can really reflect changes in water quality and better achieve water quality assessment for the study area. In addition, water quality assessment results show that major excessive factors in the study area are total nitrogen and total phosphorus; the polluting type is organic pollution; water quality varies greatly with seasons

    Modeling and Control of A Two-bus System With Grid-forming and Grid-following Converters

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    Preparation of a Smart and Portable Film for in Situ Sensing of Iron Microcorrosion

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    Corrosion of iron-containing materials, which presents serious economic and safety problems, normally begins with microcorrosion, which refers to the early stages of corrosion before visible changes appear on the surface. If microcorrosion could be detected and repaired immediately, corrosion damage could be greatly reduced. Current technology and materials, however, are not able to detect microcorrosion of iron in a cheap and convenient manner. Here, we have used a natural product, ellagic acid (EA), to fabricate an EA-functionalized poly­(vinyl alcohol) (PVA) film (EAF) for in situ sensing of the initial stage of microcorrosion. EAF was able to effectively sense iron microcorrosion via an obvious color change. The film also had good long-term stability and mechanical strength. Since EAF can be easily prepared from inexpensive and green raw materials, the film opens up a new opportunity for the detection of iron microcorrosion
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